As part of our BBSRC-funded sLoLa project ‘Creating and comprehending the circuitry of life: precise biomolecular design of multi-centre redox enzymes for a synthetic metabolism’, the Anderson and Curnow labs in the School of Biochemistry at the University of Bristol are now recruiting two 3 year PDRA posts in de novo protein design. For full details, please see the below job adverts and the links provided.
Please note that more positions in ultrafast spectroscopy (Bristol) and de novo protein design (Portsmouth) will be advertised shortly.
PDRA1 – Anderson lab
A postdoctoral research position in de novo protein and enzyme design is available for 36 months in the School of Biochemistry at the University of Bristol, supported by the BBSRC Grant BB/W003449/1, Creating and comprehending the circuitry of life: precise biomolecular design of multi-centre redox enzymes for a synthetic metabolism. The project is a collaboration between Dr Ross Anderson, Prof Adrian Mulholland, Dr Tom Oliver, Dr Paul Curnow (University of Bristol), Prof Julea Butt (UEA), Dr Bruce Lichtenstein (Portsmouth) and Dr Amandine Marechal (UCL).
The multidisciplinary project aims to construct single and multi-centre redox and light harvesting proteins and enzymes, photocatalytic de novo enzymes, and artificial respiratory complexes, providing an unprecedented framework to better understand and exploit the exceptional properties of the natural electron and energy conducting machinery.
The postdoctoral research associate will work on designing soluble redox proteins and assemblies for electron transfer, light harvesting and catalysis, and will initially focus on the construction of discrete cofactor-binding modules to serve as a platform for more complex binary and chain-containing architectures. They will also work closely with other researchers on the project, combining expertise in membrane protein design, biomolecular simulation, chemical synthesis and spectroscopy towards the construction of artificial respiratory complexes and functional components for bionanotechnology.
Further details of the BBSRC grant can be found here: https://circuitsoflife.uk, and more information on Ross Anderson’s group can be found at: https://theandersonlab.com
The advert can be found on jobs.ac.uk via the following link: https://www.jobs.ac.uk/job/CPG428/research-associate
PDRA2 – Curnow lab
A postdoctoral research position in de novo membrane protein design is available for 36 months in the School of Biochemistry at the University of Bristol, supported by the BBSRC Grant BB/W003449/1, Creating and comprehending the circuitry of life: precise biomolecular design of multi-centre redox enzymes for a synthetic metabolism. The project is a collaboration between Dr Ross Anderson, Prof Adrian Mulholland, Dr Tom Oliver, Dr Paul Curnow (University of Bristol), Prof Julea Butt (UEA), Dr Bruce Lichtenstein (Portsmouth) and Dr Amandine Marechal (UCL).
The multidisciplinary project aims to construct single and multi-centre redox and light harvesting proteins and enzymes, photocatalytic de novo enzymes, and artificial respiratory complexes, providing an unprecedented framework to better understand and exploit the exceptional properties of the natural electron and energy conducting machinery.
The postdoctoral research associate will work on designing cofactor-binding membrane proteins and assemblies for electron transfer, light harvesting and catalysis. The ambition is to establish a suite of modular designs that can interact with soluble enzymes to create more complex binary and chain-containing architectures. They will also work closely with other researchers on the project, combining expertise in membrane protein design, biomolecular simulation, chemical synthesis and spectroscopy towards the construction of artificial respiratory complexes and functional components for bionanotechnology and bioengineering.
Further details of the BBSRC grant can be found here: https://circuitsoflife.co.uk. More information on Paul Curnow’s research can be found at https://tinyurl.com/pcurnow and Ross Anderson’s group can be found at: https://theandersonlab.com
The advert can be found on jobs.ac.uk via the following link: https://www.jobs.ac.uk/job/CPG474/research-associate
Anderson Lab 